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Welcome to the November issue of The Ophthalmologist. Upfront includes news on how the Mediterranean diet protects against AMD, reports on a study on whether ILM peels really improve outcomes in ERM surgery, and the use of OCT-A for monitoring, diagnosing and staging glaucoma. In My View features Philip Rosenfeld on the importance of getting clinical trial designs right – getting it wrong impacts everyone – and Ivan Goldberg highlights the issue of patient non-adherence in glaucoma management. Our cover feature sees BJ Dupps herald a revolution in refractive surgery, driven by precision corneal biometry, biomechanics, and computer simulation. In Practice sees Paul Tornambe review pneumatic retinopexy, and in NextGen, Luca Gualdi describes an electrifying new workout for the ciliary muscles as an early presbyopia treatment. Profession sees Dawn Sim explain why ophthalmology needs to see the bigger picture and implement new technologies to improve patient care, and finally, we Sit Down With co-inventor of OCT, and totally COOL guy, David Huang.