Basic & Translational Research

Fusing the embryos of mice, where one contains a marker of its lineage, is a well-established technique in developmental biology research. The stripy corneas were still a surprise, though…

Transgenic mouse studies have revealed a signaling pathway that’s central to Schlemm’s canal formation

Limbal relaxing incisions were a large part of my approach to treating astigmatism in patients undergoing cataract surgery. No longer…

We look to the oldest in society to understand the contribution of poor nutrition to ophthalmic disease

Identifying corneal limbal stem cells for transplantation has been a major challenge. But now a highly specific marker of these cells has been found: ABCB5

SIRT1 appears to be an anti-aging protein that protects against weight gain, diabetes, inflammation, and even optic neuritis… in mouse models. Is SIRT1 the key to eternal youth, or simply snake oil?

Oral replacement therapy of the retinoid intermediate that fails to form in some types of Leber congenital amaurosis shows significant promise in an early-phase clinical trial

Might you soon take a skin cell from a patient with retinitis pigmentosa, roll it back to a pluripotent state, culture it to become retinal cells and trial gene therapy on it in vitro?

The body’s own regulatory T-lymphocytes, known as Tregs, can be taught to douse inflammation.

Sitting Down With Alice McPherson,founder of the Retina Research Foundation