Blinded by the Light
How blue light can induce retinal cell death
Phoebe Harkin |
As a child, you may have been told, “Don’t spend so long in front of the TV… your eyes will go square!” – but what if the truth was more serious? A team at the University of Toledo, OH, USA, has found that blue light emitted by digital devices – and the sun – could permanently affect eyesight.
The research, led by Ajith Karunarathne, found that, when exposed to photoexcitation by blue light, the photoreceptor chromophore 11-cis retinal (11CR) and its photoproduct, all-trans-retinal (ATR), could irreversibly distort PIP2 (a plasma membrane-bound phospholipid), disrupting downstream signaling and inducing oxidative damage, ultimately leading to cell death (Figure 1)(1).
Read the full article now
Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!
Or register now - it’s free and always will be!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Ophthalmologist magazine
Or Login via Social Media
By clicking on any of the above social media links, you are agreeing to our Privacy Notice.