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The Ophthalmologist / Issues / 2026 / September / The Anatomy of Disagreement
Anterior Segment Cornea Discussion

The Anatomy of Disagreement

The second Global Consensus on Keratoconus and Ectatic Diseases records what 128 experts from six continents now agree on. But what they don't agree on forms a map of everything the field still cannot standardize, and why

By Farhad Hafezi, José A. P. Gomes , Renato Ambrósio Jr., Mark Hillen 9/25/2026 4 min read

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Objective:

To present the findings and disagreements from the second Global Consensus on Keratoconus and Ectatic Diseases.

Approach:
  • Consensus Formation: The consensus was formed through four structured Delphi rounds and a face-to-face meeting, involving 12 ophthalmologists from various societies.
  • Key Topics Covered: The consensus addressed diagnosis, staging, cross-linking, keratoplasty, refractive surgery, and cataract surgery in keratoconic eyes.
Key Findings:
  • 91.7% of the diagnostic panel agreed that Kmax has low repeatability and reproducibility for evaluating progression, yet 75% still use Kmax in daily practice.
  • A new category, 'suspicious keratoconus,' was defined for close monitoring without a formal diagnosis.
  • There was no consensus on the use of corneal biomechanics or genetic testing in clinical decision-making.
Interpretation:

The disagreements highlight significant limitations and uncertainties in the definitions and clinical practices surrounding keratoconus management.

Limitations:
  • The consensus reflects a lack of agreement on definitions and clinical practices, which may hinder effective management.
  • Insufficient longitudinal studies exist to support the use of new technologies in clinical decision-making, impacting the reliability of the consensus.
Conclusion:

The document serves as a reference for future guidance while acknowledging areas of contention that require further research.

Sources:
  • Cornea Journal

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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