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The Ophthalmologist / Issues / 2026 / April / Optimizing the Ocular Surface Before and After Cataract Surgery
Discussion Anterior Segment Cataract

Optimizing the Ocular Surface Before and After Cataract Surgery

The role of perfluorohexyloctane in dry eye management

By Justin Schweitzer 4/8/2026 3 min read

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Clinical Scorecard: Optimizing the Ocular Surface Before and After Cataract Surgery

At a Glance

CategoryDetail
ConditionDry Eye Disease (DED)
Key MechanismsUse of perfluorohexyloctane ophthalmic solution (PFHO) to stabilize ocular surface and improve dry eye symptoms.
Target PopulationPatients undergoing cataract surgery with dry eye disease.
Care SettingOphthalmology clinics and surgical centers.

Key Highlights

  • PFHO treatment did not negatively affect refractive outcomes.
  • Significant improvement in ocular surface health and dry eye symptoms.
  • Postoperative best-corrected visual acuity (BCVA) improved with continued PFHO therapy.
  • High percentage of patients achieved optimal IOL calculation accuracy post-treatment.
  • PFHO therapy resulted in normalization of OSDI scores by study end.

Guideline-Based Recommendations

Diagnosis

  • Assess dry eye symptoms and ocular surface health preoperatively.

Management

  • Utilize PFHO for managing dry eye before and after cataract surgery.

Monitoring & Follow-up

  • Monitor ocular surface health and visual outcomes post-surgery.

Risks

  • Consider potential impacts of untreated dry eye on surgical outcomes.

Patient & Prescribing Data

Patients with severe dry eye symptoms undergoing cataract surgery.

PFHO can be administered four times daily for 30 days pre- and postoperatively without compromising surgical measurements.

Clinical Best Practices

  • Optimize ocular surface health before cataract surgery.
  • Continue dry eye treatment postoperatively to enhance visual outcomes.
  • Evaluate and document changes in ocular surface metrics and patient-reported outcomes.

References

  • Study on PFHO and Dry Eye Management

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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