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Subspecialties Pediatric, Imaging & Diagnostics, Health Economics and Policy, Comprehensive

The Big See

At a Glance

  • Approaches for diagnosing and treating pediatric and adult intraocular and ocular surface tumors differ, but advanced techniques are increasingly being used for both patient groups
  • Treatment approaches include brachytherapy, proton beam radiotherapy, photodynamic therapy (PDT), and chemotherapy depending on the type, size and location of the tumor
  • For pediatric retinoblastoma, local cryotherapy or laser treatment and brachytherapy plaques can be used for smaller tumors; chemotherapy approaches are used for more advanced cases, given systemically, into the ophthalmic artery or vitreous cavity.
  • Application of virtual clinics and artificial intelligence has the potential to pick up suspicious lesions at an earlier stage – and to make the referral process much more streamlined.

The eye can develop a range of primary or secondary tumors: some are more common in adults, while others are more typical of children. We therefore adopt somewhat different investigational approaches for the pediatric and adult populations; in both groups of patients, taking a detailed medical and ophthalmic history, performing a thorough examination and using imaging are key to correct diagnosis and management. These patients are best managed as part of a multi-disciplinary team of professionals.

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About the Author

Mandeep Sagoo

Professor of Ophthalmology and Ocular Oncology at UCL Institute of Ophthalmology and Consultant Ophthalmic Surgeon at Moorfields Eye Hospital and at Barts Health NHS Trust, London, UK. Visiting Professor at Byers Eye Institute, Stanford University, USA.

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