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Subspecialties Neuro-ophthalmology, Retina, Glaucoma, Basic & Translational Research

(Re)Generation Game

Retinal ganglion cells extend their axons (nerve fibers) to the brain via the optic nerve to process visual information. When these axons are injured, the damage is usually irreversible – but it may be possible to stimulate regeneration with the help of the adaptor molecule protrudin. Researchers at the University of Cambridge used a cell culture system to grow brain cells in a dish, then injured the axons and analyzed the response using live-cell microscopy. Their findings? Increasing the amount or activity of protrudin in these cells vastly increased their ability to regenerate.

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About the Author

Phoebe Harkin

Associate Editor of The Ophthalmologist

I’ve always loved telling stories. So much so, I decided to make a job of it. I finished a Masters in Magazine Journalism and spent three years working as a creative copywriter before itchy feet sent me (back)packing. It took seven months and 13 countries, but I’m now happily settled on The Ophthalmologist, where I’m busy getting stuck into all things eyeballs.

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