Electrical stimulation of neural responses can significantly improve outcomes for retinitis pigmentosa patients
Jim Taylor | | Longer Read
At a Glance
- Dysfunction and death of retinal cells, and consequent vision loss, can be inhibited by direct electrical stimulation of vulnerable cells in the visual pathway
- We achieve this effect not by invasive, bulky implants that generate unnatural visual stimuli, but by intravitreal injection of a colloidal suspension of nanoparticle devices that support natural vision
- These “quantum dots” diffuse into the retina where they transduce visible light energy into electricity, thereby triggering action potentials in adjacent neural cells and preserving function
- Our initial field of focus is retinitis pigmentosa; we are following encouraging Phase I results with a controlled, 15-patient clinical trial, expected to be complete by the end of 2020.
While I have been involved in ophthalmology since 1999, my career in the medical device industry started with CAT scanners as well as ultrasound machines and other devices in fields including cardiology, critical care and anesthesia. I migrated into ophthalmology in the laser therapeutic space as President of Coherent Medical, and have been in the field ever since. I’m now at a point in life where I try to spend my time only on developing new technologies that will make a significant difference to patients – opportunities that can truly change healthcare for the better. With some much recent innovation, where might we find such step-change opportunities in ophthalmology today?
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