Connect 4

Last month, we wrote that the NIH-funded Marclab for Connectomics at the John A. Moran Eye Center at the University of Utah, had published a paper presenting the first ultrastructural pathoconnectome of early neurodegeneration (1). Though the pathoconnectome has been modeled on early-stage retinitis pigmentosa, its implications go far beyond the eye and could be helpful in developing treatments for conditions including epilepsy, Alzheimer’s, Parkinson’s disease, and amyotrophic lateral sclerosis. Rebecca Pfeiffer, a Postdoc Research Associate at the Moran Eye Center, tells us more about the project and its implications for the field.