Objective:

To emphasize the importance of early recognition and treatment escalation in managing neurotrophic keratitis (NK) to prevent permanent visual impairment, including corneal scarring and perforation.

Key Findings:

• Early recognition of NK is crucial to prevent progression and visual impairment.
• CAM is effective in promoting corneal nerve regeneration and epithelial healing.
• Cenegermin may cause temporary worsening of symptoms but is beneficial for nerve growth.
• Patient education and addressing financial barriers are essential for successful treatment, as they enhance adherence.

Interpretation:

Effective management of NK requires a proactive approach, including early diagnosis, appropriate treatment selection, and ongoing patient support to mitigate the risk of severe complications.

Limitations:

• NK is often underdiagnosed due to subtle symptoms.
• Insurance delays can hinder timely access to recommended therapies, particularly for cenegermin.

Conclusion:

Prompt and decisive treatment of NK, combined with patient education and addressing systemic issues such as insurance barriers, is vital for successful outcomes.