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The Ophthalmologist / Issues / 2026 / March / Expanding the Therapeutic Landscape in Wet Agerelated Macular Degeneration
Retina Research & Innovations Discussion

Expanding the Therapeutic Landscape in Wet Age-related Macular Degeneration

The role of TKIs and sustained‑release delivery

By Hasenin Al-Khersan 3/20/2026 4 min read

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  • Top Institutions
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Top Institutions in Ophthalmology

Rankings are based on known institutional leadership in ophthalmology research, clinical trials in retinal diseases, and pioneering work in AMD therapeutics, including anti-VEGF and novel molecular therapies.

  • #1

    Bascom Palmer Eye Institute

    Miami, FL

    Bascom Palmer is consistently ranked as the top ophthalmology center in the US, with extensive clinical trials and research programs focused on AMD and retinal diseases, including pioneering anti-VEGF therapy development and novel drug delivery systems.

    Key Differentiators

    • Ophthalmology
    • Retina
    • Clinical Research
  • #2

    Massachusetts Eye and Ear Infirmary

    Boston, MA

    Massachusetts Eye and Ear is renowned for its translational research in retinal diseases and has contributed significantly to understanding AMD pathobiology and developing innovative treatments including bispecific antibodies and TKIs.

    Key Differentiators

    • Ophthalmology
    • Retina
    • Translational Research
  • #3

    Johns Hopkins Wilmer Eye Institute

    Baltimore, MD

    Wilmer Eye Institute is a leader in molecular and clinical research on retinal diseases, with a focus on innovative therapeutic approaches for AMD including anti-VEGF agents and intracellular signaling inhibitors.

    Key Differentiators

    • Ophthalmology
    • Retina
    • Molecular Medicine
  • #4

    University of California, San Francisco (UCSF) Medical Center

    San Francisco, CA

    UCSF has a strong ophthalmology department with significant contributions to AMD research, including clinical trials of anti-VEGF therapies and novel agents targeting multiple pathways involved in wet AMD.

    Key Differentiators

    • Ophthalmology
    • Retina
    • Clinical Trials
  • #5

    Mayo Clinic

    Rochester, MN

    Mayo Clinic is recognized for its comprehensive ophthalmology services and research in retinal diseases, including clinical evaluation of sustained-release therapies and multi-target inhibitors for wet AMD.

    Key Differentiators

    • Ophthalmology
    • Retina
    • Clinical Research

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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