5 Key Takeaways

• 1

  A post-hoc meta-analysis examined the influence of iris color on the efficacy of low-dose atropine in myopia management.

• 2

  The study found that children with non-brown irides showed significantly less myopia progression with atropine 0.01% compared to placebo.

• 3

  No significant treatment effect was observed in children with brown irides treated with atropine 0.01%, suggesting potential reduced efficacy.

• 4

  Atropine 0.05% did not show iris color-related differences in efficacy, indicating higher concentrations may overcome potential limitations.

• 5

  The findings raise questions about tailoring atropine dosing based on iris color, though the authors caution against immediate practice changes.