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The Ophthalmologist / Issues / 2026 / January / Tackling Trachoma in Ethiopia
Anterior Segment Health Economics and Policy News

Tackling Trachoma in Ethiopia

FLAME trial: Can a mild steroid reduce trichiasis relapse after surgery?

1/30/2026 1 min read

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Objective:

To evaluate the effectiveness of low-potency topical steroid fluorometholone in reducing postoperative trachomatous trichiasis (PTT) after corrective eyelid surgery.

Key Findings:
  • Cumulative PTT incidence at 12 months was identical in both treatment arms at 13.4%.
  • Safety assessments showed no significant rise in intraocular pressure or cataract progression.
  • Patient satisfaction with surgery was over 99%.
Interpretation:

Fluorometholone does not reduce the incidence of postoperative trachomatous trichiasis and is not cost-effective for programmatic use.

Limitations:
  • The study was limited to a specific geographic region, which may affect generalizability.
  • The intervention's effectiveness may vary based on surgical technique and training.
Conclusion:

Improving surgical outcomes for trachomatous trichiasis may rely more on surgical techniques and training rather than postoperative steroid drops.

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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