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The Ophthalmologist / Issues / 2026 / April / Permanent J-Code for Epioxa
Business and Entrepreneurship Health Economics and Policy Latest News

Permanent J-Code for Epioxa

Glaukos secures permanent J-code from CMS ahead of July rollout

4/22/2026 2 min read

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Objective:

To simplify billing and reimbursement for Epioxa, a corneal cross-linking therapy for keratoconus, while enhancing market access.

Approach:
    Key Findings:
    • The J-code aims to enhance payer acceptance and reimbursement workflows.
    • Epioxa is indicated for epithelium-on corneal collagen cross-linking in adults and pediatric patients aged 13 and older.
    • The therapy avoids epithelial removal, reducing pain and recovery time compared to traditional methods.
    • Common adverse reactions include conjunctival hyperemia, corneal haze, photophobia, punctate keratitis, eye pain, irritation, tearing, and transient reduction in visual acuity.
    Interpretation:

    The J-code is expected to improve market access and patient care for keratoconus, a condition that is often underdiagnosed and under-treated, potentially leading to better outcomes.

    Limitations:
    • Reimbursement gains depend on individual payer adoption of the new code.
    • Common adverse reactions include conjunctival hyperemia, corneal haze, and transient visual acuity reduction.
    Conclusion:

    The CMS decision strengthens the infrastructure for Epioxa's rollout in the US, potentially improving access for patients and surgeons.

    Sources:
    • BusinessWire

    This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.

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