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We are proud to present to you our second ever Takeover Issue, prepared this year with Wills Eye Hospital in Philadelphia, USA. Check out the front cover feature, written by Wills specialists, detailing how the COVID-19 pandemic has affected their fields, including ocular oncology, ophthalmic research, and trauma. Our Upfront section features the latest research and news coming from Wills Eye. In the monthly opinion column, In My View, Douglas M. Wisner explains what it takes to train the next generation of residents, and Jonathan Myers argues that it has never been easier or more affordable to identify undiagnosed glaucoma patients. The In Practice articles discuss uveitis identification, treating the skull base, and a novel portable head-mounted perimeter. For NextGen, Wills Eye Retina Service specialists Allen Ho and Carl Regillo share the cutting-edge research coming from the hospital, while in Profession, Tara A. Uhler, Laura J. Heinmiller and John Cropsey describe how the residency program at Wills instils competence, confidence and a life-long passion for the field. Finally, we sit down with Wills Eye’s Jose Pulido. I hope you enjoy reading this issue!