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Welcome to the April edition of The Ophthalmologist, our 2022 Power List issue! Following Mariya Moosajee’s editorial letter, you’ll find the latest research and industry updates in Upfront – from how spaceflight affects vision, to the future of artificial vision, right to the latest chronicle of history in ophthalmology with our resident historian ophthalmologist Andrzej Grzybowski. In this issue’s In My View section, Christian Jones discusses how nanotechnology can provide solutions to ophthalmic drug delivery, and Ivan Gabrić talks about using a combination of EDoF and diffractive multifocal optics for presbyopia. This month’s cover feature is the immensely popular annual Power List, featuring ophthalmology’s 100 biggest names, as voted for by our readers, and ranked by an independent panel of experts. Finally, we Sit Down With… Andrii Ruban, vitreoretinal specialist and President of the Ukrainian Vitreoretinal Society in Kyiv, Ukraine.