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Subspecialties Basic & Translational Research, Cataract

Pump Up the Volume

Many attempts have been made over the years to help reduce the occurrence of posterior capsule opacification (PCO) after cataract surgery. Lens epithelial cells (LECs) are the target: anything that inhibits their migration to (and proliferation on) the posterior capsule will help. Square-edged IOLs were a great step forward; they formed a physical barrier to LEC migration – but alas, given enough time, that barrier will be breached.

Over the years, a number of approaches have been made, including capsular polishing, the bag-in-the-lens procedure, and leaving the capsular bag open. The latter seems to work… but people have always speculated why? 

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About the Author

Mark Hillen

I spent seven years as a medical writer, writing primary and review manuscripts, congress presentations and marketing materials for numerous – and mostly German – pharmaceutical companies. Prior to my adventures in medical communications, I was a Wellcome Trust PhD student at the University of Edinburgh.

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