Pump Up the Volume
Why do “open bag” IOLs reduce PCO?
Mark Hillen |
Many attempts have been made over the years to help reduce the occurrence of posterior capsule opacification (PCO) after cataract surgery. Lens epithelial cells (LECs) are the target: anything that inhibits their migration to (and proliferation on) the posterior capsule will help. Square-edged IOLs were a great step forward; they formed a physical barrier to LEC migration – but alas, given enough time, that barrier will be breached.
Over the years, a number of approaches have been made, including capsular polishing, the bag-in-the-lens procedure, and leaving the capsular bag open. The latter seems to work… but people have always speculated why?
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