Subscribe to Newsletter
Subspecialties Cornea / Ocular Surface

Ocular surface: what’s new?

Dry eye disease (DED) is a particular burden for both doctor and patient alike. There are three principal reasons behind this: high prevalence (up to 100 million people worldwide are thought to be affected by DED to some degree), many causes (autoimmune, environmental, drug adverse events, and ocular and systemic disease) with multiple forms (principally aqueous-deficient and evaporative). From the ophthalmologist’s perspective, the presence of DED precludes patients from receiving surgery, complicates recovery after surgical procedures, and can present with symptoms of discomfort, visual disturbance, and tear film instability – leading to patients who are constantly unhappy with how their eyes feel.

DED is frequently characterized by increased osmolarity of the tear film and inflammation of the ocular surface, which without intervention, can ultimately result in permanent damage. Poor eyelid hygiene or impaired function of the meibomian glands can also cause or exacerbate inflammation and ocular surface damage. Because of DED’s many and multifactorial etiologies, there’s a wide range of therapeutic options in use – from lubricants to immunomodulators, and treatment needs to be individualized to each patient. However, it’s clear that DED-induced perturbations in tear film – no matter what the cause – lead to increased inflammation and visual disturbances. This supplement aims to document the issues involved in DED; its causes, its  effect on the tear film – and vision – and how this situation can be improved with topical eyedrops containing a bioprotectant like trehalose.


A new paradigm in dry eye disease

The MEIBUM survey: a closer look at the eyelids

What is trehalose?

Visual function impairment in dry eye disease

New treatment to improve tear film thickness in dry eye disease

Download the pdf here
Receive content, products, events as well as relevant industry updates from The Ophthalmologist and its sponsors.

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

About the Author
Mark Hillen

I spent seven years as a medical writer, writing primary and review manuscripts, congress presentations and marketing materials for numerous – and mostly German – pharmaceutical companies. Prior to my adventures in medical communications, I was a Wellcome Trust PhD student at the University of Edinburgh.

Related Case Studies
The Missing Piece of the Dry Eye Puzzle

| Contributed by Quidel

Uncovering Ocular Comorbidity

| Contributed by Quidel

Finding Ocular Surface Inflammation

| Contributed by Quidel

Related Product Profiles
Subspecialties Cornea / Ocular Surface
Tear Osmolarity – Empowering. Established. Essential.

| Contributed by TearLab

Subspecialties Cornea / Ocular Surface
Preservative-Free Cyclosporine 0.1% Ophthalmic Emulsion

| Contributed by ImprimisRx

Product Profiles

Access our product directory to see the latest products and services from our industry partners

Register to The Ophthalmologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine



The Ophthalmologist website is intended solely for the eyes of healthcare professionals. Please confirm below: