Cookies

Like most websites The Ophthalmologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Subspecialties Other, Basic & Translational Research

Night Guard

It’s well understood that pupil size can be dictated by surrounding light conditions and attentional states during wakefulness, but how do pupils behave during sleep? A research group from the University of Geneva in Switzerland had recently observed that their laboratory mice often slept with their eyes open under certain conditions and decided to study how pupil dynamics evolve during sleep. They found that pupil size changed rhythmically when the mice were asleep (Figure 1), and corresponded with sleep states (NREM and REM) (1). Hypothesizing that pupil size varies during sleep to protect the eyes from light stimulus that might interrupt slumber, the authors plan to pursue their studies in humans. Corresponding author, Daniel Huber, tells us more…

How did you track pupil behavior?

For this study, we developed a novel optical pupil tracking system for mice in which an infrared LED was apposed to the head of the animal. The invisible light from this LED travels through the skull and brain, and finally illuminates the back of the eye. When the eyes were imaged with an infrared camera, the pupils appeared as bright circles. This novel illumination method was easy to implement, it tracked the pupil accurately and facilitated tracking even under conditions where the eyelid is partly closed.

Read the full article now

Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

About the Author

Ruth Steer

Register to The Ophthalmologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine

Register