New Virus, Old Story
Why are patients with AMD at greater risk of developing severe COVID-19?
Aleksandra Jones | | Hot Topic
A recent paper in Nature has found a connection between the severity of COVID-19 – and the risk of dying from the disease – and mutations in genes responsible for complement and coagulation (1).
Complement, one of the oldest parts of the immune system, enhances the way antibodies deal with pathogens and damaged cells, removing them from the body and stimulating inflammation. Patients with AMD, which is caused by overactive complement, may develop more serious complications of COVID-19, resulting in more hospitalizations and deaths in this patient group.
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