Investigating the Inner Layer
Research Fellow Alice Davidson shares how discoveries in the genetics of corneal dystrophies are leading to new therapeutic avenues
Aleksandra Jones | | Interview
How and why did you get into the genetics of Fuchs’ dystrophy?
Fuchs’ endothelial corneal dystrophy (FECD) is the most common corneal dystrophy, affecting up to 4.5 percent of individuals over 50 years of age. It is an inherited, age-related, degenerative condition that primarily affects the innermost layer of the cornea and it is the most frequent indication for corneal transplantation in the developed world. Corneal transplantation is currently the only treatment option available for patients experiencing visual loss. However, these are invasive procedures that rely upon specialist facilities and healthy donor corneas, of which there is currently a global shortage. With life expectancy rapidly increasing, age-related conditions such as FECD are placing an increasing burden on healthcare systems, so we are looking for innovative (donor tissue independent) and preventative therapies to address this global healthcare need.
Read the full article now
Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!
Or register now - it’s free and always will be!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Ophthalmologist magazine
Or Login via Social Media
By clicking on any of the above social media links, you are agreeing to our Privacy Notice.