Cookies

Like most websites The Ophthalmologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Subspecialties Glaucoma

Glaucoma Diagnosis: Measuring Up to Expectations

At a Glance

  • Current methods of glaucoma evaluation may fail patients in the early stage of the disease
  • Application of OCT technology to measure multiple parameters improves the sensitivity and specificity of glaucoma diagnosis and monitoring
  • In particular, measurement of the Bruch’s membrane opening-minimum rim width (BMO-MRW) can provide a clear indication of glaucomatous tissue loss, especially when it corresponds with findings from other measurements
  • Use of multiple modalities to assess multiple retinal substructures may therefore assist physicians in assessing challenging patients and borderline diagnoses.

Traditionally, glaucoma diagnosis has relied on subjective assessments of optic nerve head (ONH) damage and/or measurements of visual field loss by automated perimetry. Though automated perimetry may use more objective scoring systems and algorithms, these can be unreliable – especially in the earlier, asymptomatic stages of disease, where nerve fiber loss may not translate into a detectable impairment in visual function.

The “hit and miss” nature of glaucoma diagnosis results in many patients remaining unrecognized and, therefore, being deprived of vision-preserving treatments. Similarly, where diagnostic techniques are insufficiently sensitive to detect markers of disease progression, patients may not have their treatment appropriately modulated in response to advancing disease.

Imaging tools and techniques able to reliably detect early glaucoma or identify patients for treatment intensification would be of great benefit to patients and public health.

Read the full article now

Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

  1. BC Chauhan et al., Ophthalmology 120, 535–543 (2013). PMID: 23265804.
  2. BC Chauhan et al., Ophthalmology, 122, 1786–1794 (2015). PMID: 26198806.

About the Author

Sanjay Asrani

Sanjay Asrani is a glaucoma specialist at Duke Eye Center at Cary, Cary, NC, USA.

Register to The Ophthalmologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine

Register