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Subspecialties Glaucoma, Glaucoma

ECP Explained

At a Glance

  • Many surgical approaches focus on reducing IOP by improving outflow
  • Cyclophotocoagulation reduces inflow – and thus IOP – by decreasing aqueous production  
  • Endoscopic cyclophotocoagulation (ECP) directly targets the ciliary processes for treatment via an ab interno approach
  • Gain top tips from my own experiences, and learn how ECP has benefited my patients.

Glaucoma is epidemic worldwide – and the number of people affected is set to increase to 79.6 million by 2020 – 74 percent of which will have open angle glaucoma (OAG) (1). Although a multifactorial disease, the primary treatment approach is IOP reduction to prevent further damage to the optic nerve. First-line therapy with topical hypotensive medications is effective when used according to direction; however, these can be limited by poor compliance or insufficient efficacy. It’s why multiple surgical IOP-lowering treatment options are also available and in development, each of which targets different outflow and filtration pathways (see Surgical management of IOP). Of these, treatments that target aqueous production are gaining in popularity.

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About the Author

Brian Francis

Brian Francis is holder of the Rupert and Gertrude Stieger Chair in Vision Research, and Professor of Ophthalmology at the Doheny Eye Institute and Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA..

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