Two studies demonstrate the safety and potential of decentered corneal collagen cross linking
Roisin McGuigan |
Corneal collagen cross linking (CXL) with ultraviolet (UV)-A light and riboflavin is a well-established treatment for corneal ecstasias and keratoconus. But are we using it to its full potential? This was the question pondered by Geneva and Lausanne-based researchers, who believe there are other conditions that might benefit from CXL, such as pellucid marginal degeneration and peripheral ulcers. However, these diseases require decentered, eccentric illumination profiles, meaning that partially irradiating the limbus with (potentially mutagenic) UV-A light is unavoidable. Corneal limbal stem cells are needed to repair the corneal epithelium following epi-off CXL, and damage affecting their regenerative capabilities would be detrimental to recovery. So the big question was, does UV-A light harm corneal stem cells? According to the researchers, no (1).
Read the full article now
Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!
Or register now - it’s free and always will be!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Ophthalmologist magazine
Or Login via Social Media
By clicking on any of the above social media links, you are agreeing to our Privacy Notice.