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Subspecialties Cornea/Ocular Surface

Current Treatment Options in Dry Eye Disease

sponsored by Santen

Managing dry eye disease becomes disproportionately more difficult as the severity of the disease increases: artificial tears and lubricants are not enough to help patients with severe dry eye disease. So what’s currently on offer?

The management of patients with mild-to-moderate dry eye disease (DED) is relatively simple (1): symptom control with artificial tears and lubricants. However, once DED starts to become classified as severe, it becomes much harder to control; you need to address not just the symptoms, but also the cause: inflammation.

Dampening the inflammation present in the ocular surface of patients with severe dry eye is key to achieving better outcomes. If we refer to Figure 1 – the vicious circle theory of dry eye – artificial tears and lubricants can help address the dry eye symptoms caused by the factors on the outside of the vicious circle, but they do nothing to address the disease processes at its core. Anti-inflammatory agents can get inside the vicious circle and disrupt it, resulting in a therapy that addresses the causes of DED, not just the symptoms (2).

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