Benchmarking Stargardt Disease
What does analysis of the last five years of the literature on Stargardt Disease tell us about the priorities of the field and the major contributors to it?
Mark Hillen |
Stargardt Disease an inherited form of juvenile macular degeneration that involves progressive vision loss that is currently untreatable. A number of strongly predisposing genes have been identified, and considerable basic and clinical research is currently ongoing into the disease, characterizing not only the defective genes, their mutations and dysfunction, but also potential therapeutic interventions, including stem cell and gene therapies.
To provide insight into the past and predictions for the future of the field, a series of metrics were applied to the last five years of the published literature. We asked:
What are the major topics for the field?
Which publications have the greatest impact?
How is the knowledge available online?
Who are the most prolific authors?
PubMed was searched for: Stargardt* AND (macular* OR degenerat*), with results limited to the last five years, in humans (for a clinical focus).