Cookies

Like most websites The Ophthalmologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Subspecialties Imaging & Diagnostics, Neuro-ophthalmology

Alzheimer’s Disease Peep Show

Alzheimer’s disease (AD) represents a unique challenge to researchers and clinicians – and society in general. There are a number of factors at play: much like glaucoma, it’s predominantly an age-related disease with symptoms that start to appear only after significant damage has occurred. Like with age-related macular degeneration, the societal problems are stark: caring for these patients is healthcare resource-intensive; the baby boomer generation is now getting to the age where AD is affecting large numbers of them, and this is a trend that’s set to continue for decades yet.

But unlike either eye disease, objectively diagnosing and staging AD is a huge challenge. The current standard of care is essentially documenting mental decline, and biomarker assays of the blood, urine and cerebrospinal fluid are still in the research stage. Positron emission tomography scans using radioactive tracers can take a peek at β-amyloid buildup in the brain – but that’s expensive and not always conclusive. A biopsy of the hippocampus would likely be definitive – but that’s really only available at autopsy. A reliable, objective early diagnostic tool is a huge currently unmet need for patients with AD – and would be welcomed by researchers who are attempting to develop drugs to slow or stop progression.

Read the full article now

Log in or register to read this article in full and gain access to The Ophthalmologist’s entire content archive. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

Register to The Ophthalmologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Ophthalmologist magazine

Register