1. Cigarette smoke causes more oxidative stress and tissue damage to the human cornea than heated tobacco products (HTPs).
2. Exposure to cigarette smoke severely compromised corneal epithelial integrity and impaired wound healing capacity.
3. Traditional cigarette smoke had a more detrimental impact on protein networks and cellular function compared to HTPs.
4. Ocular surface is uniquely sensitive to environmental toxins.
5. Smoking is a modifiable risk factor for corneal diseases.
6. Heated tobacco products may pose a lower risk of ocular damage compared to traditional cigarettes. 7. Quitting smoking remains the most reliable strategy to avoid smoke-related complications.