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Welcome to the October issue of The Ophthalmologist! You’ll find the latest research in Upfront –everything from the a curious case of blindness to building a bionic eye. This October’s In My View section features leading experts speaking on current hot topics in ophthalmology: Rajendra Apte makes the case for biomarkers in glaucoma management and Stephen Odaibo discusses the truth of the future of AI. This month’s cover feature sees many leading experts look to the changing future and provide their key insights on adjustable lens technologies. In Practice sees Erin Shriver make a global call to action to fellow ophthalmologists to recognize – and help – patients affected by IPV. In NextGen, Bala Ambati and Sneha Konda review the current literature for PACK-CXL. Finally, we Sit Down With Carol Shields, Chief of the Ocular Oncology Service at Wills Eye Hospital and Professor of Ophthalmology at Thomas Jefferson University, Philadelphia, PA, USA.