The Power List 2018
Medical Director, Centre for Sight, East Grinstead, UK
Sheraz was amongst the first in the UK to perform LASIK, and he has pioneered a number of corneal and anterior segment techniques and invented several ophthalmic instruments.
What motivates you?
“It’s really curiosity that motivates me – asking a question or encountering a problem, and then going out there to find the solution. I have a considerable dislike for dogmatic thinking and process and confess that when I find flaws, I do challenge them using fundamentals as a basis.”
What’s the future of corneal transplantation?
“Corneal transplantation has changed considerably over the last 15 years and many of those changes are thanks to technology derived from refractive surgery! Microkeratomes enabled Descemet’s stripping endothelial keratoplasty (DSAEK), which ended up evolving into Descemet’s membrane endothelial keratoplasty (DMEK). I expect both procedures will be replaced by therapeutic modalities, such as corneal cell therapies with Rho Kinase inhibitors. Stromal substitutes are already in development and I expect synthetic corneas will become more commonplace. Stem cell treatments will have a role, so long as the correct concoction of cytokines and growth factors can be found to get stem cells recruited from the bone marrow and provide the necessary repairs required.”
Resurrecting the Cornea
Ignore the Gurus and Follow the Evidence