The first three papers describing OCT angiography (OCT-A) didn’t examine the vasculature of the eye with the technology, they examined blood flow in the outer layers of the brains of rats (1)(2)(3). It was actually the fourth that examined the human eye; in 2012, Jia et al. (4) compared optic nerve head (ONH) flow in patients with preperimetric glaucoma (PPG; n=4) with normal subjects (n=4), and found that ONH flow was significantly lower in the PPG group.
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